The two clubs are in the midst of very different seasons, with Saints lodged in the relegation zone after yet another disappointing weekend defeat – although the cup did provide some breathing space with the quarter-final win over Manchester City in particular .
Sitting in the Champions League places, Newcastle have not reached the final of this competition since 1976 as they seek to end a decades-long wait for a major trophy.
Date, kick-off time and venue
Southampton vs Newcastle is set to kick off at 8pm GMT tonight, Tuesday 24th January 2023.
The game will take place at St Mary’s Stadium.
Where to watch Southampton vs Newcastle
TV channel: In the UK, the game will be shown live on Sky Sports Main Event and Football, with coverage starting at 7pm tonight.
Direct: Fans can also watch the match live online via the Sky go app.
Southampton vs Newcastle Team News
Southampton vs Newcastle prediction
The Magpies are on a relentless march this season and could get into the final with a convincing display.
Newcastle win, 1-0.
Head-to-head history and results (h2h)
The Saints have won one of their last 11 meetings.
Southampton win: 38
Newcastle win: 43
Southampton vs Newcastle match odds
Odds via Betfair (subject to change).