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NFL pick, Week 2 forecast: 49ers crush Eagles;  Bengals, Colts, Giants continue to upset

It’s only Week 2, but there are only three games between undefeated teams on the NFL schedule.

Two of these games are in the NFC. The San Francisco 49ers travel to Philadelphia in what could be one of the most entertaining games of the day. The 49ers are a road favorite worth watching. New Orleans travels to Carolina for a clash between NFC rivals. Will Jameis Winston build on an impressive Week 1 performance?

The third game will be determined by Monday night’s winner. Las Vegas meets Pittsburgh, and the highly anticipated Sunday night soccer game between Kansas City and Baltimore features another round of Patrick Mahomes versus Lamar Jackson.

Each week, Sporting News will select matches directly. Here’s how we did last week:

Week 1: 10-5, .667 (before Monday’s game)

With that in mind, here are our picks and predictions for Week 2:

NFL POWER RANKINGS: Big bumps for the Steelers and Saints, but what about this NFC West?

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NFL picks, predictions for week 2

  • New York Giants vs. Washington Football Team (-4)

Thursday, 8:20 p.m., NFL Network

It’s a 0-1 team battle, and Taylor Heinicke could be Washington’s starter after Ryan Fitzpatrick was injured in Week 1. Saquon Barkley gets more runs in this game, which is a defensive fight in the game. maximum. The Giants make six in a row in this NFC East series.

To take: Giants 20, Washington 18

  • New England Patriots (-4) vs. New York Jets

Sunday, 1 p.m., CBS

It’s a rookie quarterback battle in Mac Jones and Zach Wilson, and it’s a question of which quarterback can be the most effective. Wilson completed 54.1% of his passes and took sacks in Week 1. Jones completed 74.4% and took a sack. The Patriots win a close game.

To take: Patriots 20, Jets 17

  • Denver Broncos (-6) vs. Jacksonville Jaguars

Sunday, 1 p.m., CBS

Is the Urban Meyer era already under threat? It’ll be a challenge against Denver’s Teddy Bridgewater, who had the second-highest Week 1 completion percentage at 77.8. Jacksonville needs more than a running game behind Carlos Hyde and James Robinson. Still, it’s the home opener or Trevor Lawrence, and we think he’s delivering a moment to remember.

To take: Jaguar 21, Bronco 20

MORE: The Worst NFL overreactions Week 1

NFL pick, Week 2 forecast: 49ers crush Eagles;  Bengals, Colts, Giants continue to upset
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  • Buffalo Bills (-3.5) vs. Miami Dolphins

Sunday, 1 p.m., FOX

The Bills were upset in Week 1, making an AFC East road clash against an improved Dolphins side more urgent. Josh Allen is 5-1 as a starter against Miami.

To take: Tickets 28, Dolphins 24

  • San Francisco 49ers (-3.5) vs. Philadelphia Eagles

Sunday, 1 p.m., FOX

It’s one of the few NFC clashes between 1-0 teams, and the 49ers looked like a Super Bowl contender with a healthier squad. Deebo Samuel and George Kittle will create lags and San Francisco will build an early lead. The Eagles rushed for 173 yards in Week 1. San Francisco will make that job a lot more difficult.

To take: 49ers 28, Eagles 21

  • Los Angeles Rams (-4.5) vs. Indianapolis Colts

Sunday, 1 p.m., FOX

The Colts dominated possession time in Week 1 but just couldn’t complete touchdown practice. Matthew Stafford had a stellar debut with the Rams, but it’s one of those time zone trap games that could lead to a tighter-than-expected game. The Rams have been a .500 team on the road for the past two seasons.

To take: Colts 28, Rams 26

MORE: Rookie QB Week 1 Debut Rating

NFL pick, Week 2 forecast: 49ers crush Eagles;  Bengals, Colts, Giants continue to upset
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  • Las Vegas Raiders vs. Pittsburgh Steelers (-6.5)

Sunday, 1 p.m., CBS

The Steelers silenced some critics with a key win over Buffalo in Week 2. Now they get the Raiders in a short week. Look for rookie running back Najee Harris for better results in his second game, and TJ Watt will start the pass rush.

To take: Steelers 30, Raiders 20

  • Cincinnati Bengals vs Chicago Bears (-3.5)

Sunday, 1 p.m., FOX

The Bengals still have some work to do, but there is a belief around No.1 pick Joe Burrow that manifested itself in the overtime win over the Vikings. Chicago must switch Justin Fields from role player to starter to trigger the same chain reaction. Instead, Burrow will engage in a duel with former Bengals quarterback Andy Dalton. Ja’Marr Chase is playing the hero role again, and the Bengals are the surprise team 2-0 at the start.

To take: Bengals 26, Bear 23

  • Houston Texans vs Cleveland Browns (-12.5)

Sunday, 1 p.m., CBS

The Browns lost a heart-wrenching opener to the Chiefs, but Baker Mayfield proved the Super Bowl contender’s hype was justified. Tyrod Taylor, who Mayfield replaced in Cleveland, returns with a lesser supporting cast. This is the type of game the Browns should control from start to finish.

To take: Brown 33, Texans 20

NFL pick, Week 2 forecast: 49ers crush Eagles;  Bengals, Colts, Giants continue to upset
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  • New Orleans Saints (-3) vs. Carolina Panthers

Sunday, 1 p.m., FOX

The Saints were masterful attacking the Packers in Week 1, and Jameis Winston has proven he can perform well in a high percentage offense built around Alvin Kamara. New Orleans’ defense is also improved, and they’ll force some Sam Darnold turnovers. New Orleans is a road favorite that we love. They are 8-3 ATS as road favorites since 2019.

To take: Saints 28, Panthers 23

  • Minnesota Vikings vs Arizona Cardinals (-3.5)

Sunday, 4:05 p.m., FOX

Kyler Murray thrived in Week 1, and the Cardinals showed better defense with bookends Chandler Jones and JJ Watt. Can they win a break-in game against Minnesota which will slow the pace around Dalvin Cook? We’re going to trust Arizona.

To take: Cardinals 27, Vikings 24

  • Atlanta Falcons vs. Tampa Bay Buccaneers (-12.5)

Sunday, 4:05 p.m., FOX

Hear Tom Brady-Atlanta jokes. There won’t be a need for a giant comeback in this one. Brady averaged 394.5 passing yards in both games against the Falcons last season, and another monster game awaits him.

To take: Buccaneers 35, Falcons 24

NFL pick, Week 2 forecast: 49ers crush Eagles;  Bengals, Colts, Giants continue to upset
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  • Tennessee Titans vs. Seattle Seahawks (-5.5)

Sunday, 4:25 p.m., CBS

We’re tempted to take the Titans here because of the desperation factor, but the defense was shaky in Week 1 and Russell Wilson can replicate all of those issues for the defense. Both teams light him up in the passing game, but Seattle survives.

To take: Seahawks 32, Titans 29

  • Dallas Cowboys vs. Los Angeles Chargers (-2.5)

Sunday, 4:25 p.m., CBS

The Chargers won on the road in Game 1 and they have a chance to take Dallas down to 0-2. Justin Herbert will enjoy another 300-yard game, but Dak Prescott keeps that Dallas offense moving. As usual, the Cowboys are playing in one of the most entertaining games of the day.

To take: Cowboys 33, loaders 31

  • Kansas City Chiefs (-2.5) to Baltimore Ravens

Sunday, 8:20 p.m., NBC

The Chiefs have won the last two games in Baltimore in double digits, and Lamar Jackson is 0-3 in three career starts against Patrick Mahomes. The Chiefs have led by an halftime average of 14 points in those games. Baltimore keeps him closer, but Mahomes delivers in the clutch.

To take: Heads 31, Ravens 26

  • Detroit Lions vs. Green Bay Packers (-11.5)

Monday, 8:15 p.m., ESPN / ESPN2

The Packers didn’t look like a team that should be favored by double digits after accumulating a minimum of 229 yards in Week 1. Green Bay have won the last four games, but three of those games were decided by seven points. or less. . Detroit also struggled in a Week 1 comeback, too. Aaron Rodgers is getting the Packers back on track, but it’s not easy.

To take: Packers 31, Lions 24

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