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New schizophrenia risk genes discovered by scientists

One of the difficulties in studying the genetics of schizophrenia is its rather generic diagnostic criteria and its poor distinction from other psychotic disorders.

A new study has found genes linked to schizophrenia, according to media reports. According to the researchers, the study improves understanding of brain diseases and could lead to a new treatment.

“The motivation for this study was to better understand how rare genetic variants influence a person’s risk of developing serious mental illness, particularly schizophrenia nervosa,” said genetic psychiatrist Alexander Charney of the Icahn School of Medicine. of Mount Sinai.

The new research has shown that people with schizophrenia have more rare protein truncating variants (PTVs) than people without the disease.

Two new risk genes, SRRM2 and AKAP11, were identified in the study after comparing the genetic sequences of people with schizophrenia to those of healthy people.

Russian neurophysiologists announce discovery that will help study schizophrenia

“By focusing on a subset of genes, we discovered rare, harmful variants that could potentially lead to new drugs for schizophrenia,” said geneticist and data analyst Dongjing Liu of the Icahn School of Medicine. Mount Sinai, quoted by the media.

Schizophrenia is a mental disorder that affects approximately 24 million people, or 1 in 300 people worldwide, according to the WHO. It causes severe psychosis and a split personality, which results in hallucinations, delusions, as well as thought and behavior disturbances.

sputniknews Gt

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