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Monkeypox can spread days before any symptoms appear, study finds


https://sputniknews.com/20221103/monkeypox-may-spread-several-days-before-any-symptoms-emerge-study-shows-1103492861.html

Monkeypox can spread days before any symptoms appear, study finds

Monkeypox can spread days before any symptoms appear, study finds

There is evidence of “considerable” transmission of monkeypox in the days before symptoms of the virus appear, a study in the UK has found.

2022-11-03T06:40+0000

2022-11-03T06:40+0000

2022-11-03T07:08+0000

monkey pox

UK

US Centers for Disease Control and Prevention

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There is evidence of “considerable” transmission of monkeypox in the days before symptoms of the virus appear, a contact tracing study in the UK has found. Routine surveillance data on 2,746 people diagnosed with monkeypox in Britain between May 6 and August 1 and collected by the UK Health Security Agency (UKHSA) had been reviewed by the research team. UKHSA investigators involved in the study, details of which were published in the British Medical Association (BMAJ) journal on November 2, analyzed data from the questionnaire about the incubation period of monkeypox. They also looked at the data to estimate the so-called “series interval.” The latter is the time between the first symptoms of an individual and the appearance of symptoms in a person to whom he probably transmitted the virus. Using various mathematical models, the team found that the average serial interval was 0.3 to 1.7 days shorter than the median incubation. period, which was usually one week. As a result, the scientists concluded that a “substantial” number of cases (around 53%) were transmitted presymptomatically. After detailed analysis of 13 pairs of individuals between whom monkeypox was likely transmitted, ten of the cases appeared to show that presymptomatic transmission had occurred. In other words, the virus was likely to have been passed from person to person no more than four days before any symptoms appeared. Meanwhile, the U.S. Centers for Disease Control and Prevention (CDC) guidelines on monkeypox say people “can spread to others from the time symptoms start until the rash is completely cured”, indicating that to date “there is no evidence that monkeypox is spread from people without symptoms. Monkeypox is a rare viral disease that occurs mainly in West and Central Africa, with most people recovering within a few weeks. Early symptoms include rash, fever, headache, muscle aches, back pain, swollen lymph nodes, chills, and exhaustion. Worldwide, 77,174 people have contracted the disease in 109 countries, including 28,442 in the United States, according to the CDC. Since the first patient tested positive for the disease in early May, 3,439 confirmed cases and 146 highly probable cases of monkeypox have been recorded in the country up to September 16, 2022. UKHSA has reported a slowdown in monkeypox cases in Great Britain since August 15.

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monkeypox, symptoms, transmission, study, ukhsa, incubation period, presymptomatic transmission

monkeypox, symptoms, transmission, study, ukhsa, incubation period, presymptomatic transmission

U.S. Centers for Disease Control and Prevention (CDC) guidelines on monkeypox – a rare viral illness that occurs primarily in central and west Africa – currently state that people “can spread it to others from the moment where the symptoms start until the rash is completely healed”. .

There is evidence of “considerable” transmission of monkeypox in the days before symptoms of the virus appear, a contact tracing study in the UK has found.

Routine surveillance data on 2,746 people diagnosed with monkeypox in Britain between May 6 and August 1 and collected by the UK Health Security Agency (UKHSA) were reviewed by the research team .

UKHSA investigators involved in the study, details of which were published in the Journal of the British Medical Association (BMAJ) on November 2, analyzed the questionnaire data to estimate the incubation period for monkeypox. They also looked at the data to estimate the so-called “series interval”. The latter is the time between the first symptoms of an individual and the appearance of symptoms in a person to whom he probably transmitted the virus.

Using various mathematical models, the team found that the average serial interval was 0.3 to 1.7 days shorter than the median incubation period, which was typically one week. As a result, the scientists concluded that a “substantial” number of cases (around 53%) were transmitted presymptomatically.

After detailed analysis of 13 pairs of individuals between whom monkeypox was likely transmitted, ten of the cases appeared to show that presymptomatic transmission had occurred. In other words, the virus was likely to have been passed from person to person no more than four days before any symptoms appeared.

US awards contractor $20 million to expand distribution of Monkeypox vaccine and treatment – HHS

Meanwhile, the U.S. Centers for Disease Control and Prevention (CDC) guidelines on monkeypox state that people “can spread it to others from the time symptoms start until the rash is completely cured”, indicating that to date “there is no evidence that monkeypox is spreading”. people without symptoms.

“It is an important and potentially controversial document. It provides evidence that there may be presymptomatic transmission of monkeypox. But like any modeling paper, it still needs to be replicated and validated using other real-world data,” said Dr. Esther E Freeman, director of Global Health Dermatology at Harvard Medical School and co-author of an accompanying editorial, quoted by the United Kingdom. media.

        Colorized transmission electron micrograph of monkeypox particles (File) - Sputnik International, 1920, 02.09.2022

New ‘genetically distinct’ monkeypox strain registered in UK
Monkeypox is a rare viral disease that occurs mainly in Central and West Africa, with most people recovering within weeks. Early symptoms include rash, fever, headache, muscle aches, back pain, swollen lymph nodes, chills, and exhaustion. Worldwide, 77,174 people have contracted the disease in 109 countries, including 28,442 in the United States, according to the CDC. Since the first patient tested positive for the disease in early May, 3,439 confirmed cases and 146 highly probable cases of monkeypox have been recorded in the country up to September 16, 2022. UKHSA has reported a slowdown in monkeypox cases in Great Britain since August 15.



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