Their names were not immediately disclosed.
The incident began with a report of the first shooting, in which two people were shot dead on the northwest side of the city, IMPD spokesman Genae Cook said.
Police eventually encountered a suspect in the shooting, Cook said.
The suspect drove off and police continued until the suspect’s car pulled over, Cook said.
As per standard procedure, the five officers who fired their weapons will be placed on administrative leave while the IMPD conducts an internal investigation, Cook said.