Foden starred as England beat Andorra 5-0 on Saturday and the Manchester City midfielder is set to be rewarded with another start at Wembley tonight in what appear to be an attacking formation named by Southgate.
Mason Mount came on for the final 17 minutes against Andorra and is back in the starting XI tonight.
Mount is expected to form a three-way midfielder alongside Foden and Declan Rice, with Kalvin Phillips injured and Jude Bellingham rested from that squad.
Raheem Sterling, Harry Kane and Jack Grealish all come back in attack position, in a formidable top three.
Jordan Pickford is back in goal, while Kyle Walker and Luke Shaw return as full-backs.
With Harry Maguire injured, John Stones will team up with Tyrone Mings at center-back.
Starting England roster (4-3-3): Pickford; Walker, Stones, Mings, Shaw; Mount, Rice, Foden; Sterling, Kane, Grealish.